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TX Medical Weight Loss Center

Essays on the contents of weight loss

Reading list

Studies of composition, weight and function

The body-composition finding starts the argument. These other results give it scale, duration and complications.

Composition studies

The SURMOUNT-1 DXA substudy reports fat and lean-mass change with tirzepatide. The systematic body-composition review examines incretin therapies and the physical-function gap. For semaglutide, STEP 1 supplies the total-weight comparison and STEP 5 extends the observation over two years.

Semaglutide heart studies

The STEP-HFpEF trial concerns symptoms and physical limitations in obesity-related heart failure with preserved ejection fraction. SELECT concerns major cardiovascular events in adults with cardiovascular disease and overweight or obesity without diabetes.

Withdrawal and tolerability studies

The SURMOUNT-4 trial and its cardiometabolic analysis follow tirzepatide withdrawal. SURMOUNT-1 supplies the tirzepatide gastrointestinal finding. The semaglutide safety review and SUSTAIN-6 supply the gallbladder, rare-event and eye findings discussed here.

  1. Body composition changes during weight reduction with tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight. ↗
  2. Once-Weekly Semaglutide in Adults with Overweight or Obesity ↗
  3. Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity ↗
  4. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes ↗
  5. Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity: A Post Hoc Analysis of the SURMOUNT-4 Trial. ↗
  6. Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial. ↗
  7. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial ↗
  8. Tirzepatide Once Weekly for the Treatment of Obesity ↗
  9. Safety of Semaglutide ↗
  10. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes ↗
  11. Effect of Incretin-Based and Nonpharmacologic Weight Loss on Body Composition : A Systematic Review. ↗